Pulmonary Hypertension

endocrine hypertension :: Article Creator About The Editors Editor-in-Chief  Michael Stowasser, PhD, MBBS, FRACP, University of Queensland, Brisbane, Australia Michael is currently Director of the Hypertension Units and Co-Director of the Endocrine Hypertension Research Centre within the University of Queensland School of Medicine at Greenslopes and Princess Alexandra Hospitals in Brisbane. He has over 25 years clinical research experience in pathogenesis and management of hypertension and especially of endocrine varieties including primary aldosteronism, renovascular hypertension, pheochromocytoma and familial hyperkalemic hypertension. Working with mentor Richard Gordon, he helped to demonstrate that primary aldosteronism is at least 10 times more common than previously thought, and is the commonest specifically treatable and potentially curable form of hypertension. Ongoing studies are aimed at determining genetic bases for primary aldosteroni...

cardiac failure causes :: Article Creator Study Proposes New Heart Failure Treatment Targeting Abnormal Hormone Activity Duke-NUS scientists and their collaborators have discovered a potential new treatment for heart failure with preserved ejection fraction (HFpEF), a type of heart disease that is notoriously difficult to treat. The team discovered that the diseased heart cells had high levels of glucagon activity, a pancreatic hormone that raises blood sugar (glucose) levels. Armed with this novel insight, the scientists demonstrated that a drug that blocks the hormone's activity, can significantly improve heart function. In heart failure, which is considered a global pandemic, the heart can no longer pump blood effectively. In Singapore, heart failure is a leading cause of death, accounting for 17 percent of cardiac admissions locally. Globally, an estimated 64 million people live with this condition, with HFpEF accounting for around hal...

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idiopathic intracranial hypertension :: Article Creator Mum Of Seriously Ill Teenager Is 'fighting Losing Battle' To Get Answers The mother of a seriously unwell teenager said she is "fighting a losing battle" to get answers from medics. Keira Passey had been a happy 16-year-old when her mum Jodie Passey said she started to experience headaches. At first Jodie said the headaches were mild, but within days they became severe and debilitating. They resulted in loss of vision and balance. Following a doctor's appointment and several hospital visits, it was discovered that Keira had a rare and serious condition called Fulminant idiopathic intracranial hypertension (IIH). IIH causes high pressure around the brain and causes symptoms like brain cysts, vision changes and headaches. Fulminant IIH is a particularly severe subtype that results in severe and rapid vision loss. Patients like Keira are at a high risk for permanent vis...

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l sided heart failure :: Article Creator Treating Iron Deficiency In Patients With Heart Failure: What, Why, When, How, Where And Who Abstract For patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, iron deficiency is common and associated with more severe symptoms, worse quality of life and an increased risk of hospitalisations and death. Iron deficiency can be swiftly, effectively and safely treated by administering intravenous iron, either as ferric carboxymaltose or ferric derisomaltose, which improves patient well-being and reduces the risk of hospitalisations including those for heart failure. However, the current definition of iron deficiency in heart failure has serious flaws. A serum ferritin <100 µg/L does not identify patients more likely to respond to intravenous iron. In contrast, patients with transferrin saturations <20%, most of whom are also anaemic, are more likely to have a benefi...

pda and pulmonary hypertension :: Article Creator 1379 Fatal Enteroviral Myocarditis In 30+2 Weeks Gestation Monochorionic Diamniotic Twins Monochorionic Diamniotic twins were born at 30+2 weeks gestation by Emergency caesarean section for foetal distress in one of the twins. Mother was Gravida 3 Para 2 with no known medical illness and normal antenatal scans but was colonised with Group B Streptococcus. The twins were born in good condition but needed ventilation soon after birth. Twin 1 was extubated after 24 hours of ventilation. She deteriorated and had to be re-ventilated and was treated for possible meningitis. Her initial ECHO showed large PDA with left ventricular overload and the PDA was medically treated. She deteriorated further and ECHO at this stage showed severe left ventricular dysfunction with Pulmonary Hypertension requiring inotropes to maintain BP. ECG showed significant ST changes and troponin was significantly raised suggestin...