Pulmonary Hypertension

Liminal Biosciences's PBI-4050 Reduces Pulmonary Hypertension, Preclinical Data Show - Pulmonary Hypertension News Liminal Biosciences's PBI-4050 Reduces Pulmonary Hypertension, Preclinical Data Show - Pulmonary Hypertension News Posted: 27 Nov 2019 08:00 AM PST New preclinical data supports the positive effects of Liminal Biosciences 's lead candidate,  PBI-4050 , in reducing pulmonary hypertension and the abnormal enlargement of the heart's right ventricle muscle. The company presented its latest data on two posters at the American Heart Association 2019 conference, held recently in Philadelphia. The posters are titled " PBI-4050 Reduces Angio-proliferative Pulmonary Arterial Hypertension: Decreased Human Pulmonary Artery Smooth Muscle Cell Proliferation and Microvascular Endothelial Cell Endoplasmic Reticulum Stress, " and " Transcriptomics of Lung Molecular Remo...

Liminal Biosciences's PBI-4050 Reduces Pulmonary Hypertension, Preclinical Data Show - Pulmonary Hypertension News Liminal Biosciences's PBI-4050 Reduces Pulmonary Hypertension, Preclinical Data Show - Pulmonary Hypertension News Posted: 27 Nov 2019 08:00 AM PST New preclinical data supports the positive effects of Liminal Biosciences 's lead candidate,  PBI-4050 , in reducing pulmonary hypertension and the abnormal enlargement of the heart's right ventricle muscle. The company presented its latest data on two posters at the American Heart Association 2019 conference, held recently in Philadelphia. The posters are titled " PBI-4050 Reduces Angio-proliferative Pulmonary Arterial Hypertension: Decreased Human Pulmonary Artery Smooth Muscle Cell Proliferation and Microvascular Endothelial Cell Endoplasmic Reticulum Stress, " and " Transcriptomics of Lung Molecular Remo...

Pulmonary Hypertension, Common in TAVR Patients, Linked to Lower Survival - TCTMD Pulmonary Hypertension, Common in TAVR Patients, Linked to Lower Survival - TCTMD Posted: 26 Nov 2019 11:47 AM PST The analysis lacks the nuance, one expert says, to tease out exactly which patients with pre-interventional PH will fare poorly. LONDON, England—Patients with pulmonary hypertension (PH) undergoing TAVR for severe symptomatic aortic stenosis fare significantly worse than those without increased pre-interventional pulmonary pressures, a new analysis shows. After a mean follow-up of 31 months, patients with PH, which was defined as a mean pulmonary arterial pressure (mPAP) > 25 mm Hg, had a 60% increased risk of all-cause mortality compared with those without PH, reported Dionysios Adamopoulos, MD (Geneva University Hospital, Switzerland), last week at PCR London Valves 2019. "Pulmonary hypertension is very common in patients with aor...

In SSc, Cardiopulmonary Exercise Test May Help Detect PAH, Study Says - Scleroderma News In SSc, Cardiopulmonary Exercise Test May Help Detect PAH, Study Says - Scleroderma News Posted: 27 Nov 2019 09:00 AM PST Cardiopulmonary exercise testing (CPET), along with an algorithm that considers both lung and heart functions, can help lower the unnecessary use of right heart catheterization to determine if a scleroderma patient has pulmonary arterial hypertension , a study reports. The study, " Cardiopulmonary exercise testing in a combined screening approach to individuate pulmonary arterial hypertension in systemic sclerosis ," appeared in the journal Rheumatology . Pulmonary arterial hypertension (PAH) — a frequent and severe complication of scleroderma (SSc) — is characterized by thickening of connective tissue which narrows small arteries in the lung. This narrowing, in turn, increases pressure within pulmonary blood vessels. ...

In SSc, Cardiopulmonary Exercise Test May Help Detect PAH, Study Says - Scleroderma News In SSc, Cardiopulmonary Exercise Test May Help Detect PAH, Study Says - Scleroderma News Posted: 27 Nov 2019 09:00 AM PST Cardiopulmonary exercise testing (CPET), along with an algorithm that considers both lung and heart functions, can help lower the unnecessary use of right heart catheterization to determine if a scleroderma patient has pulmonary arterial hypertension , a study reports. The study, " Cardiopulmonary exercise testing in a combined screening approach to individuate pulmonary arterial hypertension in systemic sclerosis ," appeared in the journal Rheumatology . Pulmonary arterial hypertension (PAH) — a frequent and severe complication of scleroderma (SSc) — is characterized by thickening of connective tissue which narrows small arteries in the lung. This narrowing, in turn, increases pressure within pulmonary blood vessels. ...

Pulmonary Hypertension, Common in TAVR Patients, Linked to Lower Survival - TCTMD Pulmonary Hypertension, Common in TAVR Patients, Linked to Lower Survival - TCTMD Pulmonary arterial hypertension targeted for new treatment by Sheffield scientists - EurekAlert 7 multisystemic diseases every physician should watch for - MD Linx Pulmonary Hypertension, Common in TAVR Patients, Linked to Lower Survival - TCTMD Posted: 26 Nov 2019 11:47 AM PST The analysis lacks the nuance, one expert says, to tease out exactly which patients with pre-interventional PH will fare poorly. LONDON, England—Patients with pulmonary hypertension (PH) undergoing TAVR for severe symptomatic aortic stenosis fare significantly worse than those without increased pre-interventional pulmonary pressures, a new analysis shows. After a mean follow-up of 31 months, patients with PH, which was defined as a mean pulmonary arterial pressure (mPAP) > 25 ...