Acceleron's pulmonary hypertension treatment meets main goal, shares soar 79% - Reuters

Acceleron's pulmonary hypertension treatment meets main goal, shares soar 79% - Reuters

Acceleron's pulmonary hypertension treatment meets main goal, shares soar 79% - Reuters

Posted: 27 Jan 2020 01:36 PM PST

(Reuters) - Acceleron Pharma Inc (XLRN.O) said on Monday its investigational treatment for a rare, deadly lung disease called pulmonary arterial hypertension met the main goal in a mid-stage trial, sending its shares surging 79%.

The treatment, sotatercept, showed significant reduction in pulmonary vascular resistance versus placebo at week 24.

It also showed significant improvements in patients functional capacity, which was determined by a six minute walk test.

Pulmonary arterial hypertension, or PAH, occurs when arteries in the lungs constrict, forcing the heart to work harder, often leading to heart failure. Its symptoms include shortness of breath and fatigue.

The disease has no cure, but there are treatments on the market that can manage the condition.

The company has a rare blood disorder drug, Reblozyl, in the market.

Reporting by Dania Nadeem in Bengaluru; Editing by Shinjini Ganguli

Our Standards:The Thomson Reuters Trust Principles.

Life Hacks that Help Me to Live with PH - Pulmonary Hypertension News

Posted: 31 Jan 2020 07:00 AM PST

We don't always have a choice about what life throws our way. But our response to challenges is something we can control.

Living with pulmonary hypertension (PH), I don't always have control over my body. With that lack of control comes frustration. However, I've found some coping strategies that improve my quality of life with PH.

A chronic illness like pulmonary hypertension can affect someone in a variety of ways. Daily life with energy-depleting symptoms is taxing. Through trial and error, I have found some hacks that can help make life with PH a little simpler for me.

When discussing energy within the rare disease communities, we often mention that we are out of "spoons." For those of you unfamiliar with the "spoon theory," it comes from an essay by Christine Miserandino in which she describes how she explained to a friend her limitations while living with lupus. Like Miserandino, some days I wake up with no spoons. My main objective is to conserve my energy so that I can complete tasks planned for a particular day. But as you all know, even the best-laid plans can change.

While using these life hacks, I have noticed that I tend to have more productive days. Who doesn't like checking items off their to-do list? Some of my life hacks have proved to be beneficial while I try to balance life with PH. I set alarms on my phone as reminders to take my pills. Currently, I have four pill alarms and a pillbox that I organize each week.

I started cooking dinner as a young tween for my parents and sisters. Cooking for my family has always been an enjoyable experience for me, but the physical demands of PH have forced me to develop some strategies to continue to do that. A small foldable stool in the kitchen helps me when I'm prepping and cutting vegetables. I sometimes buy prewashed and cut fruits and vegetables if I find them at a good price. Another favorite cooking hack is my Instant Pot. This is like your grandmother's pressure cooker, but much better. I use mine to make soups, beans, chili, and shredded proteins for the week.

My local H-E-B grocer offers free, next-day delivery. Kroger stores also deliver, and they may offer coupons for a free service. If you're fortunate to be an Amazon Prime member, you can order almost anything from there — if you have a local Whole Foods, look for prime savings.

When I feel up to going out to the store, whether it's the supermarket or warehouse, I take advantage of the electric carts that are usually available. I haven't always been so open to using these carts. However, after a few attempts to shop without them, that ended in frustration and my walking out with no groceries. I gave in.

Following are other hacks that help to make my life with PH easier:

  • Dry shampoo. Yes, I went there. I carry a travel-size bottle in my bag, as I don't have the time or the energy to wash my hair as often as needed.
  • Comfy pajamas. Comfort is essential, and when you wear pajamas more often than street clothes, cuteness can't hurt either.
  • Sticky notes. Keeping some of these around the house helps me when brain fog kicks in.
  • Naps. A short snooze can be beneficial for me — and those around me.

What life hacks help to make PH life a little easier for you? Please share in the comments below. 

***

Note: Pulmonary Hypertension News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. The opinions expressed in this column are not those of Pulmonary Hypertension News or its parent company, BioNews Services, and are intended to spark discussion about issues pertaining to pulmonary hypertension.

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