Aria Raises $31M for Planned Study of Balloon Implant to Treat PAH - Pulmonary Hypertension News

Aria Raises $31M for Planned Study of Balloon Implant to Treat PAH - Pulmonary Hypertension News

Aria Raises $31M for Planned Study of Balloon Implant to Treat PAH - Pulmonary Hypertension News

Posted: 02 Mar 2020 12:00 AM PST

Aria CV announced the end of a funding round that will be used to finance a feasibility study of its medical device, the Pulmonary Hypertension System (Aria CV PH System), in people with pulmonary arterial hypertension (PAH) in the U.S.

The series B round, which raised $31 million, was led by Xeraya Capital.

"Aria CV is now well positioned to drive our clinical research forward," Dan Gladney, the company's chief executive officer and president, said in a press release.

"We are grateful for this validation by our investors and remain committed to bringing this innovative treatment option to PAH patients," Gladney added.

Pulmonary hypertension (PH) is marked by pressure in the pulmonary arteries — the blood vessels that transport blood from the heart to the lungs — rising to levels that do damage and risk heart failure. Heart muscles have to work harder to pump blood into the lungs under high pressure, and become weaker over time.

The Aria CV PH System is designed to restore pulmonary artery health and elasticity, reducing the workload on heart muscles and increasing blood flow. The device consists of a balloon surgically placed into the pulmonary artery, and inflates and deflates according to the heart cycle.

Aria is planning to open a feasibility study accessing the long-term use of the implanted device in PAH patients.

"There is an unmet clinical need with patients suffering from pulmonary arterial hypertension, and we are impressed with the promising results the Aria CV PH System has demonstrated," Jason Rushton, a partner at Xeraya Capital, said. "We look forward to being a supportive partner."

Aria's medical device recently was designated a breakthrough device by the U. S. Food and Drug Administration (FDA). The designation helps to expedite the review and potential regulatory approval of medical devices that aim to treat life-threatening or irreversibly debilitating diseases. It also offers benefits to devices' manufacturers that include additional support and feedback from the FDA.

The company expects at its device will effectively address PH symptoms, with fewer side effects than other therapies.

The device also won the Transcatheter Cardiovascular Therapeutics (TCT) 2018 Shark Tank Competition for its novelty and potential to bring change to the field of cardiovascular medicine.

Other participants in the financing round included Longview Ventures, Catalyst Health Ventures, BioStar Ventures, Cedar Point Capital, Frontcourt Group, and three strategic investors.

  • Author Details
Margarida graduated with a BS in Health Sciences from the University of Lisbon and a MSc in Biotechnology from Instituto Superior Técnico (IST-UL). She worked as a molecular biologist research associate at a Cambridge UK-based biotech company that discovers and develops therapeutic, fully human monoclonal antibodies.
Total Posts: 27
Joana holds a BSc in Biology, a MSc in Evolutionary and Developmental Biology and a PhD in Biomedical Sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — cells that made up the lining of blood vessels — found in the umbilical cord of newborns.
×
Margarida graduated with a BS in Health Sciences from the University of Lisbon and a MSc in Biotechnology from Instituto Superior Técnico (IST-UL). She worked as a molecular biologist research associate at a Cambridge UK-based biotech company that discovers and develops therapeutic, fully human monoclonal antibodies.
Latest Posts

Comments

Post a Comment

Popular posts from this blog

4 Symptoms of Stress You Should Never Ignore - AARP

Image
Vadym Pastukh/Getty Images Wins and medals aren't the only things grabbing attention at this year's Olympic games in Tokyo: Mental health awareness is also in the spotlight, after U.S. star gymnast Simone Biles' decision to withdraw from some events in order to focus on her emotional well-being.  Olympians or not, we're all susceptible to stress, whether from job or family pressures or obligations like caregiving. Here are the physical and mental signs that experts say could signal trouble.   1. Insomnia and difficulty sleeping  Can't fall or stay asleep? Insomnia is a class...
Read more

Dyspnea (Shortness of Breath): Causes, Symptoms & Treatment - my.clevelandclinic.org

Image
Overview Shortness of breath (dyspnea) is most commonly caused by heart or lung conditions. Other causes include anemia, anxiety, lack of exercise or living with obesity. What is dyspnea (shortness of breath)? Dyspnea (pronounced "DISP-nee-uh") is the word healthcare providers use for feeling short of breath. You might describe it as not being able to get enough air ("air hunger"), chest tightness or working harder to breathe. Shortness of breath is often a symptom of heart and lung problems. But it can also be a sign of other conditions like asthma, allergies or anxiety. Intense exercise or having a cold can also make you feel breathless. What are paroxysmal nocturnal dyspnea (PND) and sighing dyspnea? Paroxysmal nocturnal dyspnea (PND) is a feeling like you can't breathe an hour or two after falling asleep. Sighing dyspnea is when you sigh a lot after taking deep breaths in to try to relieve the feeling of dyspnea. What is the differ...
Read more