Industry News: Mayo Clinic collaborates with Vocalis Health for clinical development of vocal biomarkers - SelectScience

Industry News: Mayo Clinic collaborates with Vocalis Health for clinical development of vocal biomarkers - SelectScience


Industry News: Mayo Clinic collaborates with Vocalis Health for clinical development of vocal biomarkers - SelectScience

Posted: 30 Oct 2020 09:22 AM PDT

Research study intends to develop vocal biomarker for pulmonary hypertension

30 Oct 2020

Mayo Clinic and Vocalis Health, Inc., a company pioneering AI-based vocal biomarkers for use in healthcare, have announced a collaboration to research and develop new voice-based tools for screening, detecting, and monitoring patient health. The collaboration will begin with a study to identify vocal biomarkers for pulmonary hypertension (PH) which could help physicians detect and treat PH in their patients.

In a previous trial with Vocalis Health, the Mayo research team established a relationship between certain vocal characteristics and PH. In this new collaboration, Mayo will conduct a prospective clinical validation study to further develop PH vocal biomarkers. The clinical validation will utilize Vocalis Health's proprietary software, which can operate on any connected voice platform (mobile, computer, tablet, etc.), and analyzes patients' health based on voice recordings. Following this initial phase, researchers will work to identify vocal biomarkers targeting additional diseases, symptoms and conditions.

"We have seen the clinical benefits of voice analysis for patient screening throughout the COVID-19 pandemic, and this collaboration presents an opportunity for us to continue broadening our research, beginning with pulmonary hypertension," said Tal Wenderow, CEO of Vocalis Health. "Voice analysis has the potential to help physicians make more informed decisions about their patients in a non-invasive, cost-effective manner. We believe this technology could have important clinical implications for telemedicine and remote patient monitoring in the very near future. We are excited to work with Mayo Clinic and have already started planning clinical trials for additional indications."

Pulmonary hypertension is a severe condition causing high blood pressure in the lungs, but as the symptoms are similar to other heart and lung conditions, it is often not detected in routine physical exams. While traditional blood tests can sometimes detect pulmonary hypertension, it frequently goes undiagnosed. This strategic collaboration aims to provide an alternative and highly scalable method to check patients for PH, using only a recording of the patient's voice, to understand their health and the progression of the disease. 

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High blood pressure: The dizzy sensation that may indicate risk of pulmonary hypertension - Express

Posted: 06 Oct 2020 12:00 AM PDT

is the force of blood pushing against the artery walls as it goes through your body. Like air in a tyre or water in a hose, blood fills your arteries to a point. Just as too much air pressure can damage a tire, or too much water pushing through a garden hose can damage the hose, high blood pressure can hurt your arteries and lead to life-threatening conditions like stroke. Feeling breathlessness could indicate pulmonary hypertension. What is it?

Cardiologist Professor Garry Jennings, chief medical adviser of the Heart Foundation says there are dozens of causes of red faces but that high blood pressure's "not really on the list".

"That doesn't mean you can't have a red face when you've got high blood pressure, but most people don't," he says.

"But it is a tad confusing because some factors that can raise blood pressure in the short term can also give you a red face.

READ MORE: High blood pressure - sensation in the chest could be a sign

High blood pressure: Breathlessness

High blood pressure: Breathlessness could be an indication of pulmonary hypertension (Image: Getty Images)

"An ongoing problem of high blood pressure — when the force pumping blood exerts on artery walls is greater than normal — nearly always has no outward signs at all though.

"There are usually no inward signs for that matter either.

"That's the reason we're all told to have regular blood pressure checks taken by a doctor.

"However, very severe high blood pressure may cause symptoms such as headache or breathlessness."

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Breathlessness and hypertension

Shortness of breath is a tell-tale sign of the condition of pulmonary hypertension.

Pulmonary hypertension means blocked or narrowed arteries in the lungs.

As a result, the system designed to carry fresh, oxygenated blood into the left side of the heart and then to the rest of the body is affected.

Other indicators of pulmonary hypertension include fatigue, light-headedness, chest pain, racing heartbeat and swelling in the ankles or legs.

High blood pressure: GP

High blood pressure: See your GP if you have been experiencing dizziness and breathlessness (Image: Getty Images)

See a GP if you have any symptoms of pulmonary hypertension, said the NHS.

It continued: "They may ask you about your symptoms and medical history, and they may carry out a physical examination.

"Correctly diagnosing pulmonary hypertension can sometimes take time because its symptoms are similar to those of many other heart and lung conditions."

Pulmonary hypertension cannot be cured, but treatment can reduce the symptoms and help you manage your condition.

Pulmonary hypertension usually gets worse over time.

Left untreated, it may cause heart failure, which can be fatal, so its important treatment is started as soon as possible.

By following a healthy diet with a limited amount of sodium will help to reduce the risk of pulmonary hypertension.

If you have been experiencing breathlessness it's important to discuss the matter with your GP and try avoiding anything too strenuous.

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