Conditions Mistaken for Heart Failure - HealthCentral.com

Chronic kidney disease can look like heart failure. Both diseases cause fluids to backup, leading to swelling, or edema, in your lower extremities, meaning in your legs and feet. Fluid can build up in the lungs, as well, in both diseases, leading to (once again) shortness of breath. Fatigue and weakness are also common symptoms in both. "Kidney disease, getting worse, can often mimic heart failure, particularly in the context of just feeling generally poor and seeing fluid retention," says Santi Yarlagadda, M.D., a cardiologist at National Jewish Health in Denver, CO.

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